GUIDE TO DRUG

GUIDE TO DRUG, VACCINE, AND PESTICIDE USE IN AQUACULTURE (Updated: July 2007)

Appendix A - Table 1. FDA-Approved New Animal Drugs (http://www.fda.gov/cvm/drugsuseaqua.htm )

Trade name: Finquel (MS-222) NADA number: 042-427 Sponsor: Argent Laboratories, Inc. Active drug: Tricaine methanesulfonate Uses and species: Temporary immobilization of aquatic cold-blooded animals (poikilotherms), including finfish and amphibians.	Trade Name: Tricaine-S (MS-222) ANADA Number: 200-226 Sponsor: Western Chemical, Inc. Active drug: Tricaine methanesulfonate Uses and species: Temporary immobilization of aquatic cold-blooded animals (poikilotherms), including finfish and amphibians.
Trade name: Formalin-F NADA number: 137-687 Sponsor: Natchez Animal Supply Co. Active drug: Formalin Uses and species: Control of external protozoa (Chilodonella spp., Costia spp., Epistylis spp., Ichthyophthirius spp., Scyphidia spp. and Trichodina spp.), and the monogenetic trematode parasites (Cleidodiscus spp., Dactylogyrus spp.,and Gyrodactylus spp.) on all finfish. Control of fungi of the family Saprolegniaceae on all finfish eggs. Control of external protozoan parasites (Bodo spp., Epistylis spp.,and Zoothamnium spp.) on penaeid shrimp.	Trade name: Paracide-F NADA number 140-831 Sponsor: Argent Laboratories, Inc. Active drug: Formalin Uses and species: Control of external protozoa (Chilodonella spp., Costia spp., Epistylis spp., Ichthyophthirius spp., Scyphidia spp. and Trichodina spp.), and the monogenetic trematode parasites (Cleidodiscus spp., Dactylogyrus spp.,and Gyrodactylus spp.) on salmon, trout, catfish, largemouth bass, and bluegill. Control of fungi of the family Saprolegniaceae on salmon, trout, and esocid eggs.
Trade name: Parasite-S NADA number: 140-989 Sponsor: Western Chemical, Inc. Active drug: Formalin Uses and species: Control of external protozoa (Chilodonella spp., Costia spp., Epistylis spp., Ichthyophthirius spp., Scyphidia spp. and Trichodina spp.), and the monogenetic trematode parasites (Cleidodiscus spp., Dactylogyrus spp.,and Gyrodactylus spp.) on all finfish. Control of fungi of the family Saprolegniaceae on all finfish eggs. Control of external protozoan parasites (Bodo spp., Epistylis spp.,and Zoothamnium spp.) on penaeid shrimp.	Trade name: Romet 30 NADA number: 125-933 Sponsor: PharmAQ AS Active drugs: Sulfadimethoxine and ormetoprim Uses and species: Control of furunculosis in salmonids (trout and salmon) caused by Aeromonas salmonicida. Control of enteric septicemia of catfish caused by Edwardsiella ictaluri.
Trade name: Sulfamerazine in Fish Grade NADA number: 033-950 Sponsor: PharmAQ AS Active drug: Sulfamerazine Uses and species: Control of furunculosis in rainbow trout, brook trout, and brown trout. Comments: According to sponsor, this product is not presently being distributed.	Trade name: Terramycin 200 NADA number: 038-439 Sponsor: Phibro Animal Health Corp. Active drug: Oxytetracycline dihydrate Uses and species: Control of ulcer disease caused by Haemophilus piscium, furunculosis caused by Aeromonas salmonicida, bacterial hemorrhagic septicemia caused by Aeromonas liquefaciens, and pseudomonas disease in salmonids. Control of bacterial hemorrhagic septicemia caused by Aeromonas liquefaciens and pseudomonas disease in catfish. Control of gaffkemia caused by Aerococcus viridans in lobsters. Marking of skeletal tissue in Pacific salmon.
Trade name: Chorulon NADA Number: 140-927 Sponsor: Intervet, Inc. Active Drug: Chorionic gonadotropin Uses and Species: Spawning aid in all brood finfish.	Trade Name: 35% PEROX-AID NADA number: NADA 141-255 (FOI Summary at http://www.fda.gov/OHRMS/DOCKETS/98fr/2006-141-255-fois001.pdf) Sponsor: Eka Chemicals, Inc. Active drug: Hydrogen peroxide Uses and species: Control of mortality in freshwater-reared finfish eggs due to saprolegniasis; control of mortality in freshwater-reared salmonids due to bacterial gill disease associated with Flavobacterium branchiophilum; and control of mortality in freshwater-reared coolwater finfish and channel catfish due to external columnaris disease associated with Flavobacterium columnare (Flexibacter columnaris).
Trade Name: Aquaflor NADA Number: 141-246 Sponsor: Schering-Plough Active Drug: florfenicol Uses and Species: For the control of mortality in catfish due to enteric septicemia in catfish associated with Edwardsiella ictaluri; For the control of mortality in freshwater-reared salmonids due to coldwater disease associated with Flavobacterium psychrophilum; For the control of mortality in freshwater-reared salmonids due to furunculosis associated with Aeromonas salmonicida. CVM Update CVM Update	Trade Name: Aquaflor-CA1 NADA Number: 141-259 Sponsor: Schering-Plough Active Drug: florfenicol Uses and Species: for the control of mortality in catfish due to columnaris disease due to Flavobacterium columnare.
Trade name: TERRAMYCIN-343 NADA Number: NADA 008-622 Sponsor: Pfizer, Inc., Active Drug: (oxytetracycline HCl) Uses and Species: Soluble powder for skeletal marking of finfish fry and fingerlings by immersion	Trade name: Oxytetracycline HCl Soluble Powder-343 ANADA Number: ANADA 200-247 Sponsor: Phoenix Scientific, Inc., Active Drug: (oxytetracycline HCl) Uses and Species: Oxytetracycline hydrochloride for skeletal marking of all finfish fry and fingerlings by immersion
Trade name: OxyMarine NADA Number: NADA 130-435 Sponsor: Alpharma, Inc. Active Drug: (oxytetracycline HCl) Uses and Species: Oxytetracycline hydrochloride for the marking of skeletal marking of tissues of all finfish fry and fingerlings	Trade name: TETROXY Aquatic NADA Number: 200-460 Sponsor: Cross Vetpharm Group, Ltd. Active Drug: oxytetracycline hydrochloride Uses and Species: to mark skeletal tissues, most often the otoliths, of all finfish fry and fingerlings for subsequent identification.
Trade name: Terramycin 200 for Fish NADA number: 038-439 Sponsor: Phibro Animal Health Corp. Active drug: Oxytetracycline dihydrate Uses and species: Control of ulcer disease caused by Haemophilus piscium, furunculosis caused by Aeromonas salmonicida, bacterial hemorrhagic septicemia caused by Aeromonas liquefaciens, pseudomonas disease in salmonids, control of mortality in freshwater-reared salmonids due to coldwater disease caused by Flavobacterium psychrophilum, and for the control of mortality in freshwater-reared Oncorhynchus mykiss due to columnaris disease associated with Flavobacterium columnare . Control of bacterial hemorrhagic septicemia caused by Aeromonas liquefaciens and pseudomonas disease in catfish. Control of gaffkemia caused by Aerococcus viridans in lobsters. Marking of skeletal tissue in Pacific salmon.